Deep Insights with 3D Spatial Biology
Advanced chemistry, proprietary high-throughput light-sheet microscope, and AI analysis come together to deliver unmatched depth, precision, and accuracy in pathology.
Latest PR alert: LUMI redefines light-sheet microscopy with breakthrough features.
SEE WHAT YOU’VE BEEN MISSING
At Alpenglow, we offer an end-to-end solution featuring sample preparation, patented Open-Top Light-Sheet microscopy, cloud-based processing and storage, 3D visualization, and AI analysis. Our integrated technologies provide a unique 3D view of Spatial Biology—uncovering insights that are impossible or impractical with traditional 2D histology methods, from convoluted shapes and complex cell distributions to sparse objects and entire structures.
By redefining spatial biology, we are accelerating life-saving therapeutics and transforming clinical diagnostics, bringing a new dimension of clarity to science and medicine.
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Sample Preparation
Using the latest techniques to accelerate thick tissue labeling in 3D and advanced clearing methods, samples are prepared for deep imaging without affecting downstream molecular assays. Samples are mounted in custom 3D-printed holders to ensure optimal imaging quality.
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HOTLS Technology
The Hybrid Open Top Light Sheet (HOTLS) imaging platform provides optical sectioning from mesoscopic to sub-micron scales while preserving specimen integrity for further analysis. Its open-top design enables high-throughput imaging, simultaneously accommodating dozens to hundreds of samples. Controlled by LUMI, our intuitive user interface, HOTLS simplifies the imaging process and enhances real-time data visualization.
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Experience Biology in 3D
Discover biology as it was meant to be seen with cutting-edge 3D imaging, GPU-accelerated processing, and comprehensive 3D image analysis. Immerse yourself in digital pathology through advanced 3D visualization and a complete suite of analytical tools. Harness the power of machine learning and artificial intelligence to uncover deep insights and reveal what you may have been missing.
Dermatology
Explore skin tissue like never before with the 3D Derm Score Assay. Our tool provides detailed insights into skin biopsies, quantifying tissue structures like nerves and immune cells to view the epidermis and dermis comprehensively.
Immuno-Oncology
Unlock deeper insights into the TME with 3D I/O Pro profiling immune-tumor interactions at an unprecedented level. Quantify and visualize critical structures like immune cell infiltration and stromal architecture, delivering a comprehensive understanding of cancer-immune dynamics.
Multi-Field Capabilities
Our cutting-edge 3D imaging platform delivers detailed insights across diverse research areas, enabling precise quantification and visualization of complex tissue structures. From mapping intricate networks to uncovering cellular interactions, our solutions empower researchers to tackle challenges across various fields with unparalleled clarity and depth.
ABOUT ALPENGLOW
Alpenglow Biosciences accelerates drug development and improves clinical diagnostics through AI-enabled 3D imaging technology. Our platform delivers new biological insights and more accurate results by digitizing entire samples while preserving tissue for molecular analysis. Partners benefit from exclusive technology and a greater understanding of their biology. Five of the top 10 pharmaceutical companies collaborate with Alpenglow to uncover new insights, streamline timelines, and improve success rates.
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